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Index > Protein center > Tab3(Gene name) > Mouse
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  • Tab3 (Gene name),
  • TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Protein name ),  TAB3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tab3(Kiaa4135;Map3k7ip3);
    Protein name:
    TGF-beta-activated kinase 1 and MAP3K7-binding protein 3;
    Alternative:
    TAK1-binding protein 3(TAB-3);Mitogen-activated protein kinase kinase kinase 7-interacting protein 3;TGF-beta-activated kinase 1-binding protein 3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with TAB1, TAB2, MAP3K7, TRAF2 and TRAF6. The minimal TAB3-containing complex (TAB1-MAP3K7-TAB3) appears not to contain TAB2. However, it seems sensible to consider that TAB2 may also join this complex and may act in a cooperative manner with TAB3. Interacts with WDR34 (via the WD domains). Interacts with RBCK1.
    Function:
    Adapter linking MAP3K7/TAK1 and TRAF6 or TRAF2. Mediator of MAP3K7 activation, respectively in the IL-1 and TNF signaling pathways. Plays a role in activation of NF-kappa-B and AP1 transcription factor.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    716
    Sequence:
    50:
    MAQNSPQLDI | QVLHDLRQRF | PEIPEGVVSQ | CMLQNNNNLE | ACCRALSQES | 
    100:
    SKYLYMEYHS | PEDNRMNRNR | LLHINLGIHS | PSSYHPGDGA | HLNGGRTLVH | 
    150:
    SSSDGHIDPQ | HTAGKQLICL | VQEPHSAPAV | VAATPNYNPF | FMNEQNRSAA | 
    200:
    TPPSQPPQQP | SSMQTGMNPS | AMQGPSPPPP | PPSYMHIPRY | STNPITVTVS | 
    250:
    QNLPSGQTVP | RALQILPQIP | SNLYGSPGSI | FIRQTSQSSS | GRQTPQNAPW | 
    300:
    QSSPQGPVPH | YSQRPLPVYP | HQQNYQPSQY | SPKQQQIPQS | VYHSPPPSQC | 
    350:
    PSPFSSPQHQ | VQPPQLGHPS | SHVFMPPSPS | TTPPHLYQQG | PPSYQKPGSH | 
    400:
    SVAYLPYTAS | SLPKGSMKKI | EITVEPSQRP | GTAITRSPSP | ISNQPSPRNQ | 
    450:
    HSLYTATTPP | SSSPSRGISS | QPKPPFSVNP | VYITYTQPTG | PSCAPSPSPR | 
    500:
    VIPNPTTVFK | ITVGRATTEN | LLNLVDQEER | SAAPEPIQPI | SVIPGSGGEK | 
    550:
    GNHKYQRSSS | SGSDDYAYTQ | ALLLHQRARM | ERLAKQLKLE | KEELERLKAE | 
    600:
    VNSMEHDLMQ | RRLRRVSCTT | AIPTPEEMTR | LRSTNRQLQI | NVDCTLKEVD | 
    650:
    LLQSRGNFDP | KAINNFYDHI | EPGPVVPPKP | SKKDSSDSCA | IERKARRISV | 
    700:
    TSKAPVDIHD | AQAAAADEHL | SICKQSARTQ | PRDEDYEGAP | WNCDSCTFLN | 
    716:
    HPALNRCEQC | EMPRYT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Cat.:
    E2881h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Cat.:
    E2881m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Cat.:
    U2881h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Cat.:
    U2881m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Cat.:
    P2881Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Cat.:
    P2881Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Monoclonal Antibody for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Protein for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3
    Protein for Mouse TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

    R&D Technical Data
    s
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤3.9%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.7%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    91-103

    Plasma

    98

    93-106

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-105%

    90-101%

    95-105%

    92-109%

    EDTA plasma(n=5)

    89-95%

    93105%

    89-94%

    90-106%

    heparin plasma(n=5)

    93-104%

     

    94-110%

    101-111%

    91-110%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Embryonic tail.
    2. 2.
      "Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3."
      Sato Y. , Yoshikawa A. , Yamashita M. , Yamagata A. , Fukai S.
      EMBO J.28:3903-3909(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.4 ANGSTROMS) OF 688-716 IN COMPLEX WITH 'LYS-63'-LINKED DI-UBIQUITIN;NZF DOMAIN;INTERACTION WITH UBIQUITIN;SUBUNIT
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